モンシロチョウでがん細胞をやっつける！？

チョウの幼虫（いわゆるイモムシ）と，成虫では外見も食べるものも異なっている。幼虫の時期には、植物を這い回って葉っぱを食べる一方、成虫はカラフルな外見と羽を持ち，花を飛び回って蜜を吸う。このような外見の違いは，幼虫がサナギとなって成虫になるための準備をする時期に作られる。では，サナギの体の中で一体何が起きているのか？成虫には必要の無い幼虫の器官の細胞だけを壊し，成虫に必要な器官を新たに作り直していたのである。この時、重要な細胞はそのまま残し，不要な細胞だけを壊すために，モンシロチョウのサナギの体液にピエリシンという物質が分泌されていることがわかった。

形状・組織・システム:: 分解

防御・安定:: 生体組織制御

その他

チョウとがんと未知なるものと私／杉村　隆

現在の抗がん剤を用いたがん治療は、薬が正常な細胞まで攻撃してしまうという副作用のために、患者の体に大きな負担がかかる。ピエリシンでがん細胞だけを狙って攻撃できるようになれば、副作用の無い新しいがん治療方法の開発に繋がるであろう。ピエリシンを含むサナギの体液を胃がんの細胞に振りかけると、がん細胞が死滅した。ピエリシンが，がん細胞を壊すスイッチとなっていたのである。狙ったがん細胞だけを壊すことが出来るようになれば、正常な細胞を攻撃せず副作用の無い新しい抗がん剤として，将来のがん治療に役立てることができるかも知れない。

Query	Affected	Num. rows	Took (ms)	Actions
SHOW FULL COLUMNS FROM `contents`	16	16	2	maybe slow
SELECT CHARACTER_SET_NAME FROM INFORMATION_SCHEMA.COLLATIONS WHERE COLLATION_NAME= 'utf8_general_ci';	1	1	1
SHOW FULL COLUMNS FROM `users`	10	10	1	maybe slow
SHOW FULL COLUMNS FROM `groups`	4	4	1	maybe slow
SHOW FULL COLUMNS FROM `permissions`	5	5	1	maybe slow
SHOW FULL COLUMNS FROM `groups_permissions`	3	3	1	maybe slow
SHOW FULL COLUMNS FROM `groups_users`	3	3	1	maybe slow
SHOW FULL COLUMNS FROM `contents_searches`	6	6	1	maybe slow
SHOW FULL COLUMNS FROM `attachments`	11	11	1	maybe slow
SHOW FULL COLUMNS FROM `attachments_revs`	13	13	1	maybe slow
SHOW FULL COLUMNS FROM `contents_related_items`	5	5	1	maybe slow
SHOW FULL COLUMNS FROM `related_items`	6	6	1	maybe slow
SHOW FULL COLUMNS FROM `contents_related_items_revs`	8	8	1	maybe slow
SHOW FULL COLUMNS FROM `contents_tags`	5	5	1	maybe slow
SHOW FULL COLUMNS FROM `tags`	7	7	1	maybe slow
SHOW FULL COLUMNS FROM `tag_groups`	6	6	1	maybe slow
SHOW FULL COLUMNS FROM `contents_tags_revs`	7	7	1	maybe slow
SHOW FULL COLUMNS FROM `contents_revs`	18	18	1	maybe slow
SELECT `Content`.`id`, `Content`.`user_id`, `Content`.`last_edit_user_id`, `Content`.`post_date`, `Content`.`post_date_year`, `Content`.`post_date_month`, `Content`.`post_date_day`, `Content`.`title`, `Content`.`title_en`, `Content`.`content`, `Content`.`plain_content`, `Content`.`page_view`, `Content`.`flag`, `Content`.`mod_count`, `Content`.`created`, `Content`.`modified` FROM `contents` AS `Content` WHERE `id` = 172 LIMIT 1	1	1	0
SELECT `Attachment`.`file_name`, `Attachment`.`dir`, `Attachment`.`model`, `Attachment`.`foreign_key` FROM `attachments` AS `Attachment` WHERE `file_name` <> 'default.jpg' AND `Attachment`.`foreign_key` = (172)	1	1	0
SELECT `ContentsRelatedItem`.`content`, `ContentsRelatedItem`.`related_item_id`, `ContentsRelatedItem`.`content_id` FROM `contents_related_items` AS `ContentsRelatedItem` WHERE `ContentsRelatedItem`.`content_id` = (172)	10	10	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 1	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 2	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 4	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 6	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 7	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 8	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 11	1	1	0
SELECT `ContentsTag`.`id`, `ContentsTag`.`tag_group_id`, `ContentsTag`.`mod_count`, `ContentsTag`.`tag_id`, `ContentsTag`.`content_id` FROM `contents_tags` AS `ContentsTag` WHERE `ContentsTag`.`content_id` = (172)	3	3	0
SELECT `Tag`.`name`, `Tag`.`comment`, `Tag`.`tag_group_id` FROM `tags` AS `Tag` WHERE `Tag`.`id` = 51	1	1	8	maybe slow
SELECT `TagGroup`.`code`, `TagGroup`.`name` FROM `tag_groups` AS `TagGroup` WHERE `TagGroup`.`id` = 4	1	1	0
SELECT `Tag`.`name`, `Tag`.`comment`, `Tag`.`tag_group_id` FROM `tags` AS `Tag` WHERE `Tag`.`id` = 84	1	1	0
SELECT `TagGroup`.`code`, `TagGroup`.`name` FROM `tag_groups` AS `TagGroup` WHERE `TagGroup`.`id` = 6	1	1	0
SELECT `Tag`.`name`, `Tag`.`comment`, `Tag`.`tag_group_id` FROM `tags` AS `Tag` WHERE `Tag`.`id` = 175	1	1	0
SELECT `TagGroup`.`code`, `TagGroup`.`name` FROM `tag_groups` AS `TagGroup` WHERE `TagGroup`.`id` = 7	1	1	0
SELECT `RelatedItem`.`id`, `RelatedItem`.`code`, `RelatedItem`.`name`, `RelatedItem`.`created`, `RelatedItem`.`modified`, `RelatedItem`.`flag` FROM `related_items` AS `RelatedItem` WHERE `code` = 'function' LIMIT 1	1	1	0
SELECT `Content`.`id`, `Content`.`title`, `Content`.`title_en` FROM `contents` AS `Content` WHERE id = (NULL) ORDER BY `id` desc	0	0	0

Message	Memory use
Component intitailization	6.79 MB
Controller action start	6.83 MB
Controller render start	6.90 MB
View render complete	7.93 MB

Message	Time in ms	Graph
Core Processing (Derived)	299.03
Component initialization and startup	17.22
Controller action	46.78
Render Controller Action	64.91
» Rendering View	61.44
» » Rendering APP/views/contents/view.ctp	41.93
» » Rendering APP/views/layouts/default.ctp	17.76
» » » Rendering APP/views/elements/header.ctp	1.49
» » » Rendering APP/views/elements/content_sidebar.ctp	0.44
» » » Rendering APP/views/elements/footer.ctp	0.47

モンシロチョウでがん細胞をやっつける！？

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モンシロチョウでがん細胞をやっつける！？

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